New Addition Reactions. II. Addition of Aliphatic Epoxides to Schiff Bases
نویسندگان
چکیده
منابع مشابه
Chiral copper(II) complexes as Lewis acids for catalyzed cycloaddition, carbonyl addition, and conjugate addition reactions*
Bis(oxazoline) copper(II) complexes 1±3 function as enantioselective Lewis acid catalysts for carbocyclic and hetero Diels±Alder, aldol, Michael, ene, and amination reactions with substrates capable of chelation. X-ray crystallography of the catalyst reveals a propensity for the formation of distorted square planar or square pyramidal complexes. The sense of asymmetric induction is identical fo...
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The current realm of Lewis acid-promoted propargylsilane additions to carbonyl groups2 may be subdivided into two mechanistically distinct categories: (i) additions proceeding via a desilylation pathway;3 (ii) additions involving a [1,2]-silyl shift.4 Process (i) generates allenic alcohols and is most common when nonbulky silyl groups such as TMS are employed,3 whereas the latter scenario has b...
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The addition of nucleophiles to electron-deficient alkenes represents one of the more general and commonly used strategies for the convergent assembly of more complex structures from simple precursors. In this review the addition of diverse protic and organometallic nucleophiles to electron-deficient alkenes followed by enantioselective protonation is summarized. Reactions are first categorized...
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The mutagenicity of 17 aliphatic epoxides was determined using the specially constructed mutants of Salmonella typhimurium developed by Ames. The activity of these epoxides together with those reported in the literature as mutagens in strains TA100 and TA1535 depended on the degree of substitution around the oxirane ring. Monosubstituted oxiranes were the most potent mutagens in both strains. 1...
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ژورنال
عنوان ژورنال: Bulletin of the Chemical Society of Japan
سال: 1962
ISSN: 0009-2673,1348-0634
DOI: 10.1246/bcsj.35.1216